Skip to main content

Advertisement

Log in

AUGS-IUGA Joint clinical consensus statement on enhanced recovery after urogynecologic surgery

  • AUGS-IUGA JOINT PUBLICATION
  • Published:
International Urogynecology Journal Aims and scope Submit manuscript

Abstract

Introduction and hypothesis

Enhanced recovery after surgery (ERAS) evidence-based protocols for perioperative care can lead to improvements in clinical outcomes and cost savings. This article aims to present consensus recommendations for the optimal perioperative management of patients undergoing urogynecological surgery.

Methods

A review of meta-analyses, randomized clinical trials, large nonrandomized studies, and review articles was conducted via PubMed and other databases for ERAS and urogynecological surgery. ERAS protocol components were established, and then quality of the evidence was both graded and used to form consensus recommendations for each topic. These recommendations were developed and endorsed by the writing group, which is comprised of the American Urogynecologic Society and the International Urogynecological Association members.

Results

All recommendations on ERAS protocol items are based on best available evidence. The level of evidence for each item is presented accordingly. The components of ERAS with a high level of evidence to support their use include fasting for 6 h and taking clear fluids up to 2 h preoperatively, euvolemia, normothermia, surgical site preparation, antibiotic and antithrombotic prophylaxis, strong antiemetics and dexamethasone to reduce postoperative nausea and vomiting, multimodal analgesia and restrictive use of opiates, use of chewing gum to reduce ileus, removal of catheter as soon as feasible after surgery and avoiding systematic use of drains/vaginal packs.

Conclusions

The evidence base and recommendations for a urogynecology-relevant ERAS perioperative care pathway are presented in this consensus review. There are several elements of ERAS with strong evidence of benefit in urogynecological surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

Abbreviations

AUGS:

American Urogynecologic Society

BMI:

Body mass index

ERAS:

Enhanced recovery after surgery

GRADE:

Grading of recommendations, assessment, development, and evaluation

FPMRS:

Female pelvic medicine and reconstructive surgery

IPC:

Intermittent pneumatic compression

IV:

Intravenous

IUGA:

International Urogynecological Association

NSAIDs:

Nonsteroidal anti-inflammatory drugs

POI:

Postoperative ileus

PONV:

Postoperative nausea/vomiting

RCT:

Randomized control trial

SBO:

Small bowel obstruction

SDD:

Same day discharge

SSI:

Surgical site infection

VTE:

Venous thromboembolism

References

  1. Perioperative Pathways: Enhanced Recovery After Surgery [Internet]. 2018 [cited 2020 Dec 12]. Available from: https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2018/09/perioperative-pathways-enhanced-recovery-after-surgery

  2. Nelson G, Bakkum-Gamez J, Kalogera E, Glaser G, Altman A, Meyer LA, et al. Guidelines for perioperative care in gynecologic/oncology: Enhanced Recovery After Surgery (ERAS) Society recommendations—2019 update. Int J Gynecol Cancer [Internet]. 2019 Mar 15 [cited 2021 Feb 15];ijgc–2019–000356. Available from: https://ijgc.bmj.com/content/early/2019/03/15/ijgc-2019-000356

  3. Smith TW, Wang X, Singer MA, Godellas CV, Vaince FT. Enhanced recovery after surgery: A clinical review of implementation across multiple surgical subspecialties. Am J Surg. 2020;219(3):530–4.

    Article  PubMed  Google Scholar 

  4. Carter-Brooks CM, Du AL, Ruppert KM, Romanova AL, Zyczynski HM. Implementation of a urogynecology-specific enhanced recovery after surgery (ERAS) pathway. Am J Obstet Gynecol [Internet]. 2018 Nov 1 [cited 2020 Dec 12];219(5):495.e1-495.e10. Available from: https://www.ajog.org/article/S0002-9378(18)30496-4/abstract

  5. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924–6.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Boon K, Bislenghi G, D’Hoore A, Boon N, Wolthuis AM. Do older patients (> 80 years) also benefit from ERAS after colorectal resection? A safety and feasibility study. Aging Clin Exp Res. 2021;33(5):1345–52.

    Article  PubMed  Google Scholar 

  7. Tan JKH, Ang JJ, Chan DKH. Enhanced recovery program versus conventional care after colorectal surgery in the geriatric population: a systematic review and meta-analysis. Surg Endosc. 2021;35(6):3166–74.

    Article  PubMed  Google Scholar 

  8. Billquist EJ, Michelfelder A, Brincat C, Brubaker L, Fitzgerald CM, Mueller ER. Pre-operative guided imagery in female pelvic medicine and reconstructive surgery: a randomized trial. Int Urogynecology J. 2018;29(8):1117–22.

    Article  Google Scholar 

  9. Ebner F, Schulz SVW, de Gregorio A, Volz S, Steinacker JM, Janni W, et al. Prehabilitation in gynecological surgery? What do gynecologists know and need to know. Arch Gynecol Obstet [Internet]. 2018 Jan 1 [cited 2021 Jul 17];297(1):27–31. https://doi.org/10.1007/s00404-017-4565-8.

    Article  CAS  Google Scholar 

  10. Miralpeix E, Mancebo G, Gayete S, Corcoy M, Solé-Sedeño J-M. Role and impact of multimodal prehabilitation for gynecological oncology patients in an Enhanced Recovery After Surgery (ERAS) program. Int J Gynecol Cancer [Internet]. 2019 Oct 1 [cited 2022 Apr 2];29(8). Available from: https://ijgc.bmj.com/content/29/8/1235

  11. Marquini GV, Pinheiro FES, Vieira AUC, Pinto RMC, Uyeda MGBK, Girão MJBC, et al. Effects of preoperative fasting abbreviation with carbohydrate and protein solution on postoperative symptoms of gynecological surgeries: double-blind randomized controlled clinical trial. Rev Col Bras Cir. 2020;46(5):e20192295.

    Article  PubMed  Google Scholar 

  12. Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration. Anesthesiology. 2017 Mar;126(3):376–93.

  13. Svanfeldt M, Thorell A, Hausel J, Soop M, Rooyackers O, Nygren J, et al. Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole-body protein and glucose kinetics. Br J Surg. 2007;94(11):1342–50.

    Article  CAS  PubMed  Google Scholar 

  14. Noblett SE, Snowden CP, Shenton BK, Horgan AF. Randomized clinical trial assessing the effect of Doppler-optimized fluid management on outcome after elective colorectal resection. Br J Surg. 2006;93(9):1069–76.

    Article  CAS  PubMed  Google Scholar 

  15. Gustafsson UO, Nygren J, Thorell A, Soop M, Hellström PM, Ljungqvist O, et al. Pre-operative carbohydrate loading may be used in type 2 diabetes patients. Acta Anaesthesiol Scand. 2008;52(7):946–51.

    Article  CAS  PubMed  Google Scholar 

  16. Peters A, Siripong N, Wang L, Donnellan NM. Enhanced recovery after surgery outcomes in minimally invasive nonhysterectomy gynecologic procedures. Am J Obstet Gynecol. 2020;223(2):234.e1–8.

    Article  Google Scholar 

  17. Modesitt SC, Sarosiek BM, Trowbridge ER, Redick DL, Shah PM, Thiele RH, et al. Enhanced Recovery Implementation in Major Gynecologic Surgeries: Effect of Care Standardization. Obstet Gynecol. 2016;128(3):457–66.

    Article  PubMed  Google Scholar 

  18. Arnold A, Aitchison LP, Abbott J. Preoperative Mechanical Bowel Preparation for Abdominal, Laparoscopic, and Vaginal Surgery: A Systematic Review. J Minim Invasive Gynecol. 2015;22(5):737–52.

    Article  PubMed  Google Scholar 

  19. Adelowo AO, Hacker MR, Modest AM, Apostolis CA, Disciullo AJ, Hanaway KJ, et al. The Use of Mechanical Bowel Preparation in Pelvic Reconstructive Surgery: A Randomized Controlled Trial. Female Pelvic Med Reconstr Surg. 2017;23(1):1–7.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Ballard AC, Parker-Autry CY, Markland AD, Varner RE, Huisingh C, Richter HE. Bowel preparation before vaginal prolapse surgery: a randomized controlled trial. Obstet Gynecol. 2014;123(2 Pt 1):232–8.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Moawad NS, Santamaria Flores E, Le-Wendling L, Sumner MT, Enneking FK. Total Laparoscopic Hysterectomy Under Regional Anesthesia. Obstet Gynecol. 2018;131(6):1008–10.

    Article  PubMed  Google Scholar 

  22. Bailie R, Craig G, Restall J. Total intravenous anaesthesia for laparoscopy. Anaesthesia. 1989;44(1):60–3.

    Article  CAS  PubMed  Google Scholar 

  23. McGain F, Muret J, Lawson C, Sherman JD. Environmental sustainability in anaesthesia and critical care. Br J Anaesth. 2020;125(5):680–92.

    Article  CAS  PubMed  Google Scholar 

  24. Amato MBP, Meade MO, Slutsky AS, Brochard L, Costa ELV, Schoenfeld DA, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372(8):747–55.

    Article  CAS  PubMed  Google Scholar 

  25. Neto AS, Hemmes SNT, Barbas CSV, Beiderlinden M, Fernandez-Bustamante A, Futier E, et al. Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data. Lancet Respir Med. 2016;4(4):272–80.

    Article  PubMed  Google Scholar 

  26. Gali B, Bakkum-Gamez JN, Plevak DJ, Schroeder D, Wilson TO, Jankowski CJ. Perioperative Outcomes of Robotic-Assisted Hysterectomy Compared With Open Hysterectomy. Anesth Analg. 2018;126(1):127–33.

    Article  PubMed  Google Scholar 

  27. Raval AD, Uyei J, Karabis A, Bash LD, Brull SJ. Incidence of residual neuromuscular blockade and use of neuromuscular blocking agents with or without antagonists: A systematic review and meta-analysis of randomized controlled trials. J Clin Anesth [Internet]. 2020 Sep 1 [cited 2021 Oct 27];64:109818. Available from: https://www.sciencedirect.com/science/article/pii/S0952818020300362

  28. Zhao X, Tong Y, Ren H, Ding X-B, Wang X, Zong J-Y, et al. Transversus abdominis plane block for postoperative analgesia after laparoscopic surgery: a systematic review and meta-analysis. Int J Clin Exp Med [Internet]. 2014 Sep 15 [cited 2021 Jul 11];7(9):2966–75. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211820/

  29. Trowbridge ER, Evans SL, Sarosiek BM, Modesitt SC, Redick DL, Tiouririne M, et al. Enhanced recovery program for minimally invasive and vaginal urogynecologic surgery. Int Urogynecology J [Internet]. 2019 Feb [cited 2020 Dec 12];30(2):313–21. Available from: http://link.springer.com/10.1007/s00192-018-3794-0

  30. Soni N. British Consensus Guidelines on Intravenous Fluid Therapy for Adult Surgical Patients (GIFTASUP): Cassandra’s view. Anaesthesia. 2009;64(3):235–8.

    Article  CAS  PubMed  Google Scholar 

  31. Carter-Brooks CM, Romanova AL, DeRenzo JS, Shepherd JP, Zyczynski HM. Age and Perioperative Outcomes After Implementation of an Enhanced Recovery After Surgery Pathway in Women Undergoing Major Prolapse Repair Surgery. Female Pelvic Med Reconstr Surg. 2021;27(2):e392–8.

    Article  PubMed  Google Scholar 

  32. Gould MK, Garcia DA, Wren SM, Karanicolas PJ, Arcelus JI, Heit JA, et al. Prevention of VTE in Nonorthopedic Surgical Patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest [Internet]. 2012 1 [cited 2022 Jan 9];141(2, Supplement):e227S-e277S. Available from: https://www.sciencedirect.com/science/article/pii/S0012369212601251

  33. Hokenstad ED, Habermann EB, Glasgow AE, Occhino JA. Risk of venous thromboembolism in patients undergoing surgery for pelvic organ prolapse. Int Urogynecology J. 2016;27(10):1525–8.

    Article  Google Scholar 

  34. Solomon ER, Frick AC, Paraiso MFR, Barber MD. Risk of deep venous thrombosis and pulmonary embolism in urogynecologic surgical patients. Am J Obstet Gynecol. 2010;203(5):510.e1–4.

    Article  Google Scholar 

  35. Mueller MG, Pilecki MA, Catanzarite T, Jain U, Kim JYS, Kenton K. Venous thromboembolism in reconstructive pelvic surgery. Am J Obstet Gynecol. 2014;211(5):552.e1–6.

    Article  Google Scholar 

  36. Seim LA, Irizarry-Alvarado JM. Perioperative Management of Female Hormone Medications. Curr Clin Pharmacol. 2017;12(3):188–93.

    Article  CAS  PubMed  Google Scholar 

  37. Caprini JA, Arcelus JI, Hasty JH, Tamhane AC, Fabrega F. Clinical assessment of venous thromboembolic risk in surgical patients. Semin Thromb Hemost. 1991;17(Suppl 3):304–12.

    PubMed  Google Scholar 

  38. Cronin M, Dengler N, Krauss ES, Segal A, Wei N, Daly M, et al. Completion of the Updated Caprini Risk Assessment Model (2013 Version). Clin Appl Thromb Off J Int Acad Clin Appl Thromb. 2019;25:1076029619838052.

    Google Scholar 

  39. Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 Suppl):381S–453S.

    Article  CAS  PubMed  Google Scholar 

  40. Prevention of Infection After Gynecologic Procedures. ACOG Practice Bulletin No. 195. American College of Obstetricians and Gynecologists. Obstet Gynecol. 2018;131(6):e172–89.

  41. Overview | Surgical site infections: prevention and treatment | Guidance | NICE [Internet]. NICE; [cited 2021 Oct 28]. Available from: https://www.nice.org.uk/guidance/ng125

  42. Ayeleke RO, Mourad S, Marjoribanks J, Calis KA, Jordan V. Antibiotic prophylaxis for elective hysterectomy. Cochrane Database Syst Rev. 2017;6:CD004637.

    PubMed  Google Scholar 

  43. Svenningsen R, Kulseng-Hanssen S, Kråkenes EBC, Schiøtz HA. Is antibiotic prophylaxis necessary in mid-urethral sling surgery? Int Urogynecology J. 2021;32(3):629–35.

    Article  Google Scholar 

  44. Webster J, Osborne S. Preoperative bathing or showering with skin antiseptics to prevent surgical site infection. Cochrane Database Syst Rev. 2015;2:CD004985.

    Google Scholar 

  45. Tanner J, Norrie P, Melen K. Preoperative hair removal to reduce surgical site infection. Cochrane Database Syst Rev. 2011;11:CD004122.

    Google Scholar 

  46. Xu H, Wang Z, Lu Y, Guan X, Ma Y, Malone DC, et al. Value of Active Warming Devices for Intraoperative Hypothermia Prevention—A Meta-Analysis and Cost-Benefit Analysis. Int J Environ Res Public Health [Internet]. 2021 Jan [cited 2022 Jan 9];18(21):11360. Available from: https://www.mdpi.com/1660-4601/18/21/11360

  47. Hypothermia: prevention and management in adults having surgery | Guidance | NICE cg 65; 2008; last updated dec 2016 [Internet]. NICE; [cited 2021 Dec 22]. Available from: https://www.nice.org.uk/guidance/cg65/evidence

  48. Robot-Assisted Surgery for Noncancerous Gynecologic Conditions: ACOG COMMITTEE OPINION SUMMARY, Number 810. Obstet Gynecol. 2020 Sep;136(3):640–1.

  49. Lawrie TA, Liu H, Lu D, Dowswell T, Song H, Wang L, et al. Robot-assisted surgery in gynaecology. Cochrane Database Syst Rev. 2019;4:CD011422.

    PubMed  Google Scholar 

  50. Yilmaz G, Akça A, Aydin N. Enhanced recovery after surgery (ERAS) versus conventional postoperative care in patients undergoing abdominal hysterectomies. Ginekol Pol. 2018;89(7):351–6.

    Article  PubMed  Google Scholar 

  51. Topçu HO, Cavkaytar S, Kokanalı K, Guzel AI, Islimye M, Doganay M. A prospective randomized trial of postoperative pain following different insufflation pressures during gynecologic laparoscopy. Eur J Obstet Gynecol Reprod Biol. 2014;182:81–5.

    Article  PubMed  Google Scholar 

  52. Altman AD, Robert M, Armbrust R, Fawcett WJ, Nihira M, Jones CN, et al. Guidelines for vulvar and vaginal surgery: Enhanced Recovery After Surgery Society recommendations. Am J Obstet Gynecol. 2020 Oct;223(4):475–85.

    Article  PubMed  Google Scholar 

  53. Wainwright TW, Gill M, McDonald DA, Middleton RG, Reed M, Sahota O, et al. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Acta Orthop. 2020;91(1):3–19.

    Article  PubMed  Google Scholar 

  54. Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, et al. Guidelines for Perioperative Care in Elective Colonic Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations. World J Surg [Internet]. 2013 Feb 1 [cited 2020 Dec 13];37(2):259–84. Available from: https://doi.org/10.1007/s00268-012-1772-0

  55. Stone R, Carey E, Fader AN, Fitzgerald J, Hammons L, Nensi A, et al. Enhanced Recovery and Surgical Optimization Protocol for Minimally Invasive Gynecologic Surgery: An AAGL White Paper. J Minim Invasive Gynecol. 2021;28(2):179–203.

    Article  PubMed  Google Scholar 

  56. Swenson CW, Kelley AS, Fenner DE, Berger MB. Outpatient Narcotic Use After Minimally Invasive Urogynecologic Surgery. Female Pelvic Med Reconstr Surg. 2016;22(5):377–81.

    Article  PubMed  PubMed Central  Google Scholar 

  57. Reagan KML, O’Sullivan DM, Gannon R, Steinberg AC. Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial. Am J Obstet Gynecol. 2017;217(3):325.e1–325.e10.

    Article  CAS  Google Scholar 

  58. Ramaseshan AS, O’Sullivan DM, Steinberg AC, Tunitsky-Bitton E. A comprehensive model for pain management in patients undergoing pelvic reconstructive surgery: a prospective clinical practice study. Am J Obstet Gynecol. 2020;223(2):262.e1–8.

    Article  CAS  Google Scholar 

  59. Davidson ERW, Paraiso MFR, Walters MD, Propst K, Ridgeway B, Yao M, et al. A randomized controlled noninferiority trial of reduced vs routine opioid prescription after prolapse repair. Am J Obstet Gynecol. 2020;223(4):547.e1–547.e12.

    Article  CAS  Google Scholar 

  60. Linder BJ, Occhino JA, Wiest SR, Klingele CJ, Trabuco EC, Gebhart JB. Assessing the impact of procedure-specific opioid prescribing recommendations on opioid stewardship following pelvic organ prolapse surgery. Am J Obstet Gynecol. 2019;221(5):515.e1–8.

    Article  CAS  Google Scholar 

  61. Ong CKS, Seymour RA, Lirk P, Merry AF. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. Anesth Analg. 2010;110(4):1170–9.

    Article  CAS  PubMed  Google Scholar 

  62. Long JB, Bevil K, Giles DL. Preemptive Analgesia in Minimally Invasive Gynecologic Surgery. J Minim Invasive Gynecol. 2019;26(2):198–218.

    Article  PubMed  Google Scholar 

  63. Kalogera E, Glaser GE, Kumar A, Dowdy SC, Langstraat CL. Enhanced Recovery after Minimally Invasive Gynecologic Procedures with Bowel Surgery: A Systematic Review. J Minim Invasive Gynecol. 2019;26(2):288–98.

    Article  PubMed  Google Scholar 

  64. Collins SA, Joshi G, Quiroz LH, Steinberg AC, Nihira MA. Pain management strategies for urogynecologic surgery: a review. Female Pelvic Med Reconstr Surg. 2014;20(6):310–5.

    Article  PubMed  Google Scholar 

  65. Kalogera E, Nelson G, Liu J, Hu QL, Ko CY, Wick E, et al. Surgical technical evidence review for gynecologic surgery conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery. Am J Obstet Gynecol. 2018;219(6):563.e1–563.e19.

    Article  Google Scholar 

  66. Turner LC, Zyczynski HM, Shepherd JP. Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. Obstet Gynecol. 2019;133(3):492–502.

    Article  CAS  PubMed  Google Scholar 

  67. Crisp CC, Khan M, Lambers DL, Westermann LB, Mazloomdoost DM, Yeung JJ, et al. The Effect of Intravenous Acetaminophen on Postoperative Pain and Narcotic Consumption After Vaginal Reconstructive Surgery: A Double-Blind Randomized Placebo-Controlled Trial. Female Pelvic Med Reconstr Surg. 2017;23(2):80–5.

    Article  PubMed  Google Scholar 

  68. Lombardi TM, Kahn BS, Tsai LJ, Waalen JM, Wachi N. Preemptive Oral Compared With Intravenous Acetaminophen for Postoperative Pain After Robotic-Assisted Laparoscopic Hysterectomy: A Randomized Controlled Trial. Obstet Gynecol. 2019;134(6):1293–7.

    Article  PubMed  Google Scholar 

  69. Dwarica DS, Pickett SD, Zhao YD, Nihira MA, Quiroz LH. Comparing Ketorolac With Ibuprofen for Postoperative Pain: A Randomized Clinical Trial. Female Pelvic Med Reconstr Surg 2020 ;26(4):233–238.

  70. Petrikovets A, Sheyn D, Sun HH, Chapman GC, Mahajan ST, Pollard RR, et al. Multimodal opioid-sparing postoperative pain regimen compared with the standard postoperative pain regimen in vaginal pelvic reconstructive surgery: a multicenter randomized controlled trial. Am J Obstet Gynecol. 2019;221(5):511.e1–511.e10.

    Article  CAS  Google Scholar 

  71. Ni J, Jiang J, Mao S, Sun R-F. Pregabalin does not decrease acute pain or postoperative nausea and vomiting after hysterectomy: a meta-analysis. J Int Med Res. 2020 Dec;48(12):300060520954720.

    Article  PubMed  Google Scholar 

  72. Alayed N, Alghanaim N, Tan X, Tulandi T. Preemptive use of gabapentin in abdominal hysterectomy: a systematic review and meta-analysis. Obstet Gynecol. 2014;123(6):1221–9.

    Article  CAS  PubMed  Google Scholar 

  73. Yao Z, Shen C, Zhong Y. Perioperative Pregabalin for Acute Pain After Gynecological Surgery: A Meta-analysis. Clin Ther. 2015;37(5):1128–35.

    Article  CAS  PubMed  Google Scholar 

  74. Bykov K, Bateman BT, Franklin JM, Vine SM, Patorno E. Association of Gabapentinoids With the Risk of Opioid-Related Adverse Events in Surgical Patients in the United States. JAMA Netw Open [Internet]. 2020;3(12):e2031647 Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772715/.

    Article  Google Scholar 

  75. Weingarten TN, Jacob AK, Njathi CW, Wilson GA, Sprung J. Multimodal Analgesic Protocol and Postanesthesia Respiratory Depression During Phase I Recovery After Total Joint Arthroplasty. Reg Anesth Amp Pain Med [Internet]. 2015;40(4):330 Available from: http://rapm.bmj.com/content/40/4/330.abstract.

    Article  CAS  Google Scholar 

  76. Cavalcante AN, Sprung J, Schroeder DR, Weingarten TN. Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression. Anesth Analg. 2017;125(1):141–6.

    Article  CAS  PubMed  Google Scholar 

  77. Deljou A, Hedrick SJ, Portner ER, Schroeder DR, Hooten WM, Sprung J, et al. Pattern of perioperative gabapentinoid use and risk for postoperative naloxone administration. Br J Anaesth [Internet]. 2018 1 [cited 2021 Oct 31];120(4):798–806. Available from: https://www.sciencedirect.com/science/article/pii/S0007091218300382

  78. Hristovska A-M, Kristensen BB, Rasmussen MA, Rasmussen YH, Elving LB, Nielsen CV, et al. Effect of systematic local infiltration analgesia on postoperative pain in vaginal hysterectomy: a randomized, placebo-controlled trial. Acta Obstet Gynecol Scand [Internet]. 2014 [cited 2021 Oct 31];93(3):233–8. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.12319

  79. O’Neal MG, Beste T, Shackelford DP. Utility of preemptive local analgesia in vaginal hysterectomy. Am J Obstet Gynecol [Internet]. 2003 Dec 1 [cited 2021 Oct 31];189(6):1539–41. Available from: https://www.sciencedirect.com/science/article/pii/S0002937803019483

  80. Zacharakis D, Prodromidou A, Douligeris A, Hadzilia S, Kathopoulis N, Athanasiou S, et al. Pelvic floor reconstructive surgery under local anesthesia: A systematic review and meta-analysis. Neurourol Urodyn [Internet]. 2021 [cited 2021 Oct 31];40(6):1304–32. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002/nau.24691

  81. Mazloomdoost D, Pauls RN, Hennen EN, Yeung JY, Smith BC, Kleeman SD, et al. Liposomal bupivacaine decreases pain following retropubic sling placement: a randomized placebo-controlled trial. Am J Obstet Gynecol [Internet]. 2017 Nov 1 [cited 2021 Oct 31];217(5):598.e1-598.e11. Available from: https://www.ajog.org/article/S0002-9378(17)30843-8/fulltext

  82. Dengler KL, Craig ER, DiCarlo-Meacham AM, Welch EK, Brooks DI, Vaccaro CM, et al. Preoperative pudendal block with liposomal and plain bupivacaine reduces pain associated with posterior colporrhaphy: a double-blinded, randomized controlled trial. Am J Obstet Gynecol [Internet]. 2021 Nov 1 [cited 2022 Feb 17];225(5):556.e1-556.e10. Available from: https://www.sciencedirect.com/science/article/pii/S0002937821009686

  83. Jones CL, Gruber DD, Fischer JR, Leonard K, Hernandez SL. Liposomal bupivacaine efficacy for postoperative pain following posterior vaginal surgery: a randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol [Internet]. 2018 Nov 1 [cited 2021 Oct 31];219(5):500.e1-500.e8. Available from: https://www.sciencedirect.com/science/article/pii/S0002937818308214

  84. Iwanoff C, Salamon C. Liposomal Bupivacaine Versus Bupivacaine Hydrochloride with Lidocaine during Midurethral Sling Placement: A Randomized Controlled Trial. J Minim Invasive Gynecol [Internet]. 2019 [cited 2021 Oct 31];26(6):1133–8. Available from: https://www.sciencedirect.com/science/article/pii/S1553465018313554

  85. Yeung J, Crisp CC, Mazloomdoost D, Kleeman SD, Pauls RN. Liposomal Bupivacaine During Robotic Colpopexy and Posterior Repair: A Randomized Controlled Trial. Obstet Gynecol [Internet]. 2018 Jan [cited 2021 Oct 31];131(1):39–46. Available from: https://journals.lww.com/greenjournal/Fulltext/2018/01000/Liposomal_Bupivacaine_During_Robotic_Colpopexy_and.6.aspx?pid=amcampaignobgyn&wk.medium=cpc&agency=TrendMD

  86. Blanton E, Lamvu G, Patanwala I, Barron KI, Witzeman K, Tu FF, et al. Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review. Am J Obstet Gynecol [Internet]. 2017 [cited 2021 Oct 31];216(6):557–67. Available from: https://www.sciencedirect.com/science/article/pii/S0002937816464665

  87. Crisp CC, Bandi S, Kleeman SD, Oakley SH, Vaccaro CM, Estanol MV, et al. Patient-controlled versus scheduled, nurse-administered analgesia following vaginal reconstructive surgery: a randomized trial. Am J Obstet Gynecol [Internet]. 2012 Nov 1 [cited 2021 Nov 14];207(5):433.e1-433.e6. Available from: https://www.sciencedirect.com/science/article/pii/S0002937812006540

  88. Dinges H-C, Otto S, Stay DK, Bäumlein S, Waldmann S, Kranke P, et al. Side Effect Rates of Opioids in Equianalgesic Doses via Intravenous Patient-Controlled Analgesia: A Systematic Review and Network Meta-analysis. Anesth Analg [Internet]. 2019 Oct [cited 2021 Nov 14];129(4):1153–62. Available from: https://journals.lww.com/anesthesia-analgesia/Fulltext/2019/10000/Side_Effect_Rates_of_Opioids_in_Equianalgesic.37.aspx

  89. Propst K, Tunitsky-Bitton E, O’Sullivan DM, Steinberg AC, LaSala C. Phenazopyridine for Evaluation of Ureteral Patency: A Randomized Controlled Trial. Obstet Gynecol. 2016;128(2):348–55.

    Article  PubMed  Google Scholar 

  90. Sierra T, Taylor DL, Leung K, Hall CD, Flynn MK. The Effect of Phenazopyridine on Immediate Postoperative Voiding After Prolapse Surgery: A Randomized Controlled Trial. Female Pelvic Med Reconstr Surg. 2021;27(2):85–9.

    Article  PubMed  Google Scholar 

  91. Hill AM, Crisp CC, Shatkin-Margolis A, Tam T, Yook E, Kleeman S, et al. The influence of postoperative environment on patient pain and satisfaction: a randomized trial. Am J Obstet Gynecol. 2020;223(2):271.e1–8.

    Article  Google Scholar 

  92. Apfel CC, Heidrich FM, Jukar-Rao S, Jalota L, Hornuss C, Whelan RP, et al. Evidence-based analysis of risk factors for postoperative nausea and vomiting. Br J Anaesth. 2012;109(5):742–53.

    Article  CAS  PubMed  Google Scholar 

  93. Pauls RN, Crisp CC, Oakley SH, Westermann LB, Mazloomdoost D, Kleeman SD, et al. Effects of dexamethasone on quality of recovery following vaginal surgery: a randomized trial. Am J Obstet Gynecol. 2015;213(5):718.e1–7.

    Article  CAS  Google Scholar 

  94. Dewinter G, Staelens W, Veef E, Teunkens A, Van de Velde M, Rex S. Simplified algorithm for the prevention of postoperative nausea and vomiting: a before-and-after study. Br J Anaesth. 2018;120(1):156–63.

  95. Anand M, Woelk JL, Weaver AL, Trabuco EC, Klingele CJ, Gebhart JB. Perioperative complications of robotic sacrocolpopexy for post-hysterectomy vaginal vault prolapse. Int Urogynecology J. 2014;25(9):1193–200.

    Article  Google Scholar 

  96. Hedrick TL, McEvoy MD, Mythen MMG, Bergamaschi R, Gupta R, Holubar SD, et al. American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Gastrointestinal Dysfunction Within an Enhanced Recovery Pathway for Elective Colorectal Surgery. Anesth Analg. 2018;126(6):1896–907.

    Article  PubMed  Google Scholar 

  97. Diakosavvas M, Thomakos N, Psarris A, Fasoulakis Z, Theodora M, Haidopoulos D, et al. Preoperative Bowel Preparation in Minimally Invasive and Vaginal Gynecologic Surgery. ScientificWorld J. 2020;2020:8546037.

    Article  Google Scholar 

  98. Kalogera E, Van Houten HK, Sangaralingham LR, Borah BJ, Dowdy SC. Use of bowel preparation does not reduce postoperative infectious morbidity following minimally invasive or open hysterectomies. Am J Obstet Gynecol. 2020;223(2):231.e1–231.e12.

    Article  Google Scholar 

  99. Dunivan GC, Sussman AL, Jelovsek JE, Sung V, Andy UU, Ballard A, et al. Gaining the patient perspective on pelvic floor disorders’ surgical adverse events. Am J Obstet Gynecol. 2019;220(2):185.e1–185.e10.

    Article  Google Scholar 

  100. Patel M, Schimpf MO, O’Sullivan DM, LaSala CA. The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol. 2010;202(5):479.e1–5.

    Article  Google Scholar 

  101. Edenfield AL, Siddiqui NY, Wu JM, Dieter AA, Garrett MA, Visco AG. Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial. Obstet Gynecol. 2016;128(3):543–9.

    Article  CAS  PubMed  Google Scholar 

  102. Charoenkwan K, Matovinovic E. Early versus delayed oral fluids and food for reducing complications after major abdominal gynaecologic surgery. Cochrane Database Syst Rev. 2014;12:CD004508.

    Google Scholar 

  103. Gungorduk K, Paskal EK, Demirayak G, Köseoğlu SB, Akbaba E, Ozdemir IA. Coffee consumption for recovery of intestinal function after laparoscopic gynecological surgery: A randomized controlled trial. Int J Surg Lond Engl. 2020;82:130–5.

    Article  Google Scholar 

  104. Turkay Ü, Yavuz A, Hortu İ, Terzi H, Kale A. The impact of chewing gum on postoperative bowel activity and postoperative pain after total laparoscopic hysterectomy. J Obstet Gynaecol J Inst Obstet Gynaecol. 2020;40(5):705–9.

    Article  Google Scholar 

  105. Roslan F, Kushairi A, Cappuyns L, Daliya P, Adiamah A. The Impact of Sham Feeding with Chewing Gum on Postoperative Ileus Following Colorectal Surgery: a Meta-Analysis of Randomised Controlled Trials. J Gastrointest Surg [Internet]. 2020 [cited 2021 Jul 11];24(11):2643–53. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595968/

  106. Rachaneni S, Dua A. Interventions to reduce morbidity from vault hematoma following vaginal hysterectomy: a systematic review and meta-analysis. Int Urogynecology J. 2019;30(7):1061–70.

    Article  Google Scholar 

  107. Thiagamoorthy G, Khalil A, Cardozo L, Srikrishna S, Leslie G, Robinson D. The value of vaginal packing in pelvic floor surgery: a randomised double-blind study. Int Urogynecology J [Internet]. 2014 [cited 2021 Oct 31];25(5):585–91. Available from: https://doi.org/10.1007/s00192-013-2264-y

  108. Rajan P, Soundara Raghavan S, Sharma D. Study comparing 3 hour and 24 hour post-operative removal of bladder catheter and vaginal pack following vaginal surgery: a randomised controlled trial. BMC Womens Health [Internet]. 2017 Sep 11 [cited 2021 May 31];17. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594577/

  109. Xie N, Hu Z, Ye Z, Xu Q, Chen J, Lin Y. A systematic review comparing early with late removal of indwelling urinary catheters after pelvic organ prolapse surgery. Int Urogynecology J 2020 4;

  110. Carter-Brooks CM, Zyczynski HM, Moalli PA, Brodeur PG, Shepherd JP. Early catheter removal after pelvic floor reconstructive surgery: a randomized trial. Int Urogynecol J. 2018;29(8):1203–12.

    Article  PubMed  PubMed Central  Google Scholar 

  111. Hakvoort RA, Elberink R, Vollebregt A, Ploeg T, Emanuel MH. How long should urinary bladder catheterisation be continued after vaginal prolapse surgery? A randomised controlled trial comparing short term versus long term catheterisation after vaginal prolapse surgery. BJOG Int J Obstet Gynaecol. 2004;111(8):828–30.

    Article  CAS  Google Scholar 

  112. Barron KI, Savageau JA, Young SB, Labin LC, Morse AN. Prediction of successful voiding immediately after outpatient mid-urethral sling. Int Urogynecology J [Internet]. 2006 [cited 2022 Feb 17];17(6):570–5. Available from: https://doi.org/10.1007/s00192-005-0064-8

  113. Bray R, Cartwright R, Digesu A, Fernando R, Khullar V. A randomised controlled trial comparing immediate versus delayed catheter removal following vaginal prolapse surgery. Eur J Obstet Gynecol Reprod Biol. 2017 Mar;210:314–8.

    Article  PubMed  Google Scholar 

  114. Tunitsky-Bitton E, Murphy A, Barber MD, Goldman HB, Vasavada S, Jelovsek JE. Assessment of voiding after sling: a randomized trial of 2 methods of postoperative catheter management after midurethral sling surgery for stress urinary incontinence in women. Am J Obstet Gynecol. 2015;212(5):597.e1–9.

    Article  Google Scholar 

  115. Shatkin-Margolis A, Yook E, Hill AM, Crisp CC, Yeung J, Kleeman S, et al. Self-Removal of a Urinary Catheter After Urogynecologic Surgery: A Randomized Controlled Trial. Obstet Gynecol. 2019;134(5):1027–36.

    Article  PubMed  Google Scholar 

  116. Liu L, Yi J, Cornella J, Butterfield R, Buras M, Wasson M. Same-Day Discharge after Vaginal Hysterectomy with Pelvic Floor Reconstruction: Pilot Study. J Minim Invasive Gynecol. 2020;27(2):498–503.e1.

    Article  PubMed  Google Scholar 

  117. Kisby CK, Polin MR, Visco AG, Siddiqui NY. Same-Day Discharge After Robotic-Assisted Sacrocolpopexy. Female Pelvic Med Reconstr Surg. 2019;25(5):337–41.

    Article  PubMed  Google Scholar 

  118. Lloyd JC, Guzman-Negron J, Goldman HB. Feasibility of same day discharge after robotic assisted pelvic floor reconstruction. Can J Urol. 2018;25(3):9307–12.

    PubMed  Google Scholar 

  119. Hickman LC, Paraiso MFR, Goldman HB, Propst K, Ferrando CA. Same-Day Discharge After Minimally Invasive Sacrocolpopexy Is Feasible, Safe, and Associated With High Patient Satisfaction. Female Pelvic Med Reconstr Surg. 2021 Jan 4;Publish Ahead of Print.

  120. Pache B, Jurt J, Grass F, Hübner M, Demartines N, Mathevet P, et al. Compliance with enhanced recovery after surgery program in gynecology: are all items of equal importance? Int J Gynecol Cancer Off J Int Gynecol Cancer Soc. 2019;

  121. Panza J, Prescott L, Sorabella L, Dumas S, Helou C, Adam R. Compliance and outcomes after implementation of an enhanced recovery surgical protocol in older women undergoing pelvic reconstructive surgery. J Perioper Pract. 2020 Nov;30(11):352–9.

    PubMed  Google Scholar 

  122. de Groot JJ, Maessen JM, Slangen BF, Winkens B, Dirksen CD, van der Weijden T. A stepped strategy that aims at the nationwide implementation of the Enhanced Recovery After Surgery programme in major gynaecological surgery: study protocol of a cluster randomised controlled trial. Implement Sci IS. 2015;10:106.

    Article  PubMed  Google Scholar 

  123. Heathcote S, Duggan K, Rosbrugh J, Hill B, Shaker R, Hope WW, et al. Enhanced Recovery after Surgery (ERAS) Protocols Expanded over Multiple Service Lines Improves Patient Care and Hospital Cost. Am Surg. 2019;85(9):1044–50.

    Article  PubMed  Google Scholar 

  124. Nikodemski T, Biskup A, Taszarek A, Albin M, Chudecka-Głaz A, Cymbaluk-Płoska A, et al. Implementation of an enhanced recovery after surgery (ERAS) protocol in a gynaecology department - the follow-up at 1 year. Contemp Oncol Poznan Pol. 2017;21(3):240–3.

    Google Scholar 

  125. Relph S, Bell A, Sivashanmugarajan V, Munro K, Chigwidden K, Lloyd S, et al. Cost effectiveness of enhanced recovery after surgery programme for vaginal hysterectomy: a comparison of pre and post-implementation expenditures. Int J Health Plann Manage. 2014;29(4):399–406.

    Article  PubMed  Google Scholar 

  126. Weimann A, Braga M, Carli F, Higashiguchi T, Hübner M, Klek S, et al. ESPEN guideline: Clinical nutrition in surgery. Clin Nutr Edinb Scotl. 2017;36(3):623–50.

    Article  Google Scholar 

  127. Loughlin SM, Alvarez A, Falcão LFDR, Ljungqvist O. The History of ERAS (Enhanced Recovery After Surgery) Society and its development in Latin America. Rev Col Bras Cir. 2020;47:e20202525.

    Article  PubMed  Google Scholar 

  128. Elias KM. Understanding Enhanced Recovery After Surgery Guidelines: An Introductory Approach. J Laparoendosc Adv Surg Tech A. 2017;27(9):871–5.

    Article  PubMed  Google Scholar 

  129. Moonesinghe SR, Grocott MPW, Bennett-Guerrero E, Bergamaschi R, Gottumukkala V, Hopkins TJ, et al. American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on measurement to maintain and improve quality of enhanced recovery pathways for elective colorectal surgery. Perioper Med Lond Engl. 2017;6:6.

    Article  Google Scholar 

  130. Butler K, Yi J, Wasson M, Klauschie J, Ryan D, Hentz J, et al. Randomized controlled trial of postoperative belladonna and opium rectal suppositories in vaginal surgery. Am J Obstet Gynecol. 2017;216(5):491.e1–6.

    Article  CAS  Google Scholar 

  131. Yoo J-E, Oh D-S. Potential benefits of acupuncture for enhanced recovery in gynaecological surgery. Forsch Komplementarmedizin 2006. 2015;22 (2):111–6.

  132. Haya N, Feiner B, Baessler K, Christmann-Schmid C, Maher C. Perioperative interventions in pelvic organ prolapse surgery. Cochrane Database Syst Rev [Internet]. 2018 Aug 19 [cited 2021 May 31];2018(8). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513581/

Download references

Acknowledgements

The following writing group members are being recognized for their contributions to this article: Writing Group Chair: Pallavi Latthe. IUGA Writing Group Members: Pallavi Latthe (Birmingham Women’s and Children’s NHS Foundation Trust and University of Birmingham, Birmingham, UK); Gisele Vissoci Marquini (Department of Gynecology, Federal University of Uberlândia/MG (UFU) and Federal University of São Paulo (UNIFESP), São Paulo, Brazil); Chahin Achtari (CHUV-UNIL, Lausanne, Switzerland); Jorge Haddad (Division at Clinics Hospital of University of São Paulo, São Paulo, Brazil). AUGS Writing Group Members: Joseph Panza (University of Rochester Medical Center, Rochester, NY, USA); Christopher J. Jankowski (Mayo Clinic, Rochester, MN, USA); Christine A. Heisler (Departments of Ob/Gyn and Urology, University of Wisconsin, Madison, WI, USA); Krista Reagan (MultiCare Health System, Tacoma, WA, USA); Lisa C. Hickman (Division of Female Pelvic Medicine and Reconstructive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA).

The authors acknowledge Leslie Christensen, librarian at UWSC, for carrying out the systematic searches and advice on methods, and Lauren Cavendish (AUGS liason) for advice on manuscript layout, content, and other advice.

Financial disclosure

None related to this manuscript for all of the writing team

Author information

Authors and Affiliations

Consortia

Ethics declarations

Disclaimer

The joint AUGS-IUGA guidelines are an educational aid to good clinical practice. They present recognized methods and techniques of clinical practice, based on published evidence, for consideration by urogynecologists and other relevant health professionals.

The ultimate judgment regarding a particular clinical procedure or treatment plan must be made by the doctor or other attendant in the light of clinical data presented by the patient and the diagnostic and treatment options available. Departure from the local prescriptive protocols or guidelines should be fully documented in the patient’s case notes at the time the relevant decision is taken.

Conflicts of interest

None

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Individual writing group members are noted in the Acknowledgements section.

This report is being published concurrently in Urogynecology and in International Urogynecology Journal. The report is identical except for minor stylistic and spelling differences in keeping with each journal’s style. Citations from any of the two journals can be used when citing this article.

Correspondence: Pallavi Latthe, Birmingham Women’s and Children’s NHS Foundation Trust and University of Birmingham, Birmingham, UK. E-mail: platthe@nhs.net

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Developed by the Joint Writing Group of the International Urogynecological Association and the American Urogynecologic Society. AUGS-IUGA Joint clinical consensus statement on enhanced recovery after urogynecologic surgery. Int Urogynecol J 33, 2921–2940 (2022). https://doi.org/10.1007/s00192-022-05223-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00192-022-05223-4

Keywords

Navigation